Abstract: The contradiction between urbanization and odor pollution is becoming more and more serious. At present， the control technology is limited by the problems of complex odor components in landfills， many seasonal variation factors， difficult to define the changing rules and difficult to close open-air operations， which leads to bad control effect. Based on CFD simulation technology， chlorine dioxide spray oxidation deodorization technology was adopted. The spatial distribution characteristics of odor pollutants were confirmed through CFD simulation of wind field. According to the simulation results， the key spray range was selected. The wind gun was arranged to block off odor and the corresponding prevention and control measures were put forward. The equipment could be monitored in real time to control odor intelligently.