Abstract: The current situation and existing problems of municipal solid waste transport in Guangzhou was analyzed， and the transport modes with other municipal solid waste in China was compared. Combined with the actual situation and future demand of municipal solid waste transport system in Guangzhou， the optimization of solid waste transport system was studied. The recent optimization of municipal solid waste transport station in Guangzhou is mainly to improve the transport efficiency， improve environmental protection measures and upgrade the transport station. In the medium and long term， it is mainly to improve the transport efficiency and transform the waste transport mode in Guangzhou. It is suggested to adopt“large domestic waste compression and transport” as the core transport form and  adopt the combined transport mode of “large transport station mainly transport + direct collection and transport supplement”.